Fast-acting dissolution provides dispersion before being swallowed, which may provide faster metabolism. 10 ODTs may have a faster onset of action and higher bioavailability occur via blood vessels under the tongue, rather than being absorbed through the digestive tract. Absorption of drugs before reaching the stomach avoids hepatic metabolism, which can reduce the dose and may increase the bioavailability of the drug. 8 The bioavailability of drugs that are absorbed in the mouth, pharynx, and esophagus may be increased 9. The rapid disintegration of the resulting tablets may result in a quick dissolution of the drug and fast absorption that can provide a rapid onset of action. ODTs present no risk of obstruction of the gastrointestinal tract, which is beneficial for patients who do not have access to water such as patients who are traveling. Orally disintegrating tablets offer many of the advantages of solid and liquid dosage forms offer. An ODT is a solid dosage form that disintegrates and dissolves in the mouth (either on or beneath the tongue or in the buccal cavity) without water within 60 seconds or less. PDE5i Orally Disintegrating Tablets (ODT)Īn orally disintegrating tablet or orally dissolving tablet (ODT) differ from traditional tablets in that they are designed to be dissolved on the tongue rather than swallowed whole. While an injectable ED medication may sound intimidating or even painful, the truth is, the treatment involves very little discomfort and is an easy and very effective way to treat ED. The injectable medications Papaverine, Phentolamine, Alprostadil (Prostaglandin E1), and/or Atropine are used individually or in combination. 5 In those cases custom compounded medications can often be used successfully to treat ED. While some men respond well to oral ED treatments such as Viagra or Cialis, others do not respond to these treatments or have uncomfortable or even dangerous side effects to these medications. 3 Fortunately, no matter what the cause, Erectile Dysfunction can be successfully treated. It can even be the result of everyday pressures such as stress, anxiety, or just nervousness. 2 Sometimes smoking, alcohol use, or certain medications can all cause ED. Often times after prostate surgery men experience ED due to nerve damage or other trauma to the male body. For instance, men who have diabetes, decreased testosterone levels, high blood pressure, an enlarged prostate, or some other health conditions may get ED. Sometimes ED is an unfortunate side effect of a disease. 1 The majority of those men are over 40 years old, but it can strike no matter what your age. It's estimated that erectile dysfunction (ED) affects more than 18 million men in the United States alone.
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